Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep;37(5):2697-2709.
doi: 10.1002/hpm.3496. Epub 2022 May 8.

A data driven policy to minimise the tuberculosis testing cost among healthcare workers

Affiliations

A data driven policy to minimise the tuberculosis testing cost among healthcare workers

Vishnunarayan Girishan Prabhu et al. Int J Health Plann Manage. 2022 Sep.

Abstract

Introduction: The Centres for Disease Control and Prevention (CDC) mandates that healthcare employees at high-risk exposure to Tuberculosis (TB) undergo annual testing. Currently, two methods of TB testing are used: a two-step skin test (TST) or a whole-blood test (IGRA). Healthcare leadership's test selection must account for not only direct costs such as procedure and resources but also indirect costs, including employee workplace absence.

Methods: A mathematical model based on Upstate South Carolina's largest health system affecting over 18,000 employees on six campuses was developed to investigate the value loss perspective of these testing methods and assist in decision-making. A process flow map identified the varied direct and indirect costs for each test for four employee types, and 6 travel-to-testing-site times were calculated.

Results: The switching point between testing procedures that minimised total system costs was most influenced by employee salary compared to travel distance. Switching from the current hospital policy to an integrated TST/IGRA testing could reduce TB compliance costs by 28%.

Conclusions: This study recommends an integrated approach as cost-effective for large health systems with multiple campuses while considering the direct and indirect costs. When accounting for 'inconvenience costs' (stress, etc.) associated with visits, IGRAs are recommended irrespective of employee salary.

Keywords: cost analysis; decision-making; healthcare policy; mathematical modelling; tuberculosis testing.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
Skin Test (TST) process flow
FIGURE 2
FIGURE 2
Blood Test (IGRA QFT‐GIT) process flow
FIGURE 3
FIGURE 3
Assignment based on salary and travel time
FIGURE 4
FIGURE 4
Individual test cost for each combination of salary and travel time

Similar articles

References

    1. Rich AR. The Pathogenesis of Tuberculosis: C. C. Thomas; 1946.
    1. World Health Organization. Guidelines on the Management of Latent Tuberculosis Infection: WHO; 2015. - PubMed
    1. Institute of Medicine . Tuberculosis in the Workplace: National Academies Press; 2001. - PubMed
    1. Sosa LE, Njie GJ, Lobato MN, et al. Tuberculosis screening, testing, and treatment of U.S. Health care personnel: recommendations from the national tuberculosis controllers association and CDC. MMWR Morb Mortal Wkly Rep. 2019;68(19):439‐443. 10.15585/mmwr.mm6819a3 - DOI - PMC - PubMed
    1. Jensen PA, Lambert LA, Iademarco MF, Ridzon R. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health‐care settings. MMWR Recomm Rep. 2005;54(17):1‐141. Accessed July 21, 2020. https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5417a1.htm - PubMed