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. 2021 Oct-Dec;14(4):496-500.
doi: 10.4103/apc.apc_14_21. Epub 2022 Mar 25.

Pulmonary valve infective endocarditis: A case series

Satyavan Sharma  1 , Gunjan Arvindbhai Malavia  1
Affiliations

Pulmonary valve infective endocarditis: A case series

Satyavan Sharma et al. Ann Pediatr Cardiol. 2021 Oct-Dec.

Abstract

Background and objectives: Infective endocarditis (IE) involving the native pulmonary valve (PV) is extremely rare, with no data in Indian literature. The objective of this communication is to describe the clinical and diagnostic characteristics, underlying risk factors, microbiological features, and management of PVIE.

Methods: This is a retrospective analysis of 8 cases of PVIE managed in a tertiary care center from 1992 to 2020.

Results: PVIE was observed in 8 patients with underlying congenital cardiac malformation (Group A, 6 Patients) and in patients with central venous catheter (Group B, 2 patients). All the patients had prolonged febrile illness accompanied by right heart failure 4 (50%), septic pulmonary emboli 2 (25%), and pulmonary regurgitation 3 (37.5%). Trans-thoracic echocardiography demonstrated the vegetations, whereas computed tomography of chest diagnosed pulmonary emboli in 2 (25%), and pulmonary artery aneurysm in 1 (12.5%) patient. The early mortality was extremely high (5, 62.5%). Delayed diagnosis, fulminant septicemia, and multi-organ failure resulted in unfavorable outcomes.

Conclusions: IE of the native PV is a rare and potentially lethal illness. Diagnosis should be considered in any febrile patient with an underlying congenital defect, central venous line, bacteremia, and comorbidities. Multi-modality imaging should be utilized to enhance the diagnostic yield and detect complications promptly.

Keywords: Infective endocarditis; mycotic pulmonary artery aneurysm; native pulmonary valve endocarditis; pulmonary valve.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a and b) Two-dimensional echocardiography short axis view shows vegetation (veg) on pulmonary valve. The excessive mobility into RVO and PA raise the possibility of a flail leaflet. AO: Aorta, RA: Right atrium, LA: Left atrium, TV: Tricuspid valve, RVO: Right ventricular outflow, PA: Pulmonary artery
Figure 2
Figure 2
Skiagram chest pulmonary artery view shows homogenous shadow occupying large portion of right lung (Panel a). High resolution computed tomography of chest revealed a large (6.1 cm × 5.0 cm) enhancing vascular structure with surrounding low density thrombus in relation to right pulmonary artery interpreted as aneurysm (Panel b)
See this image and copyright information in PMC

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