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Review
. 1987;55(1):1-10.
doi: 10.1159/000163388.

The endothelium of the high endothelial venule: a specialized endothelium with unique properties

Review

The endothelium of the high endothelial venule: a specialized endothelium with unique properties

G Kraal et al. Exp Cell Biol. 1987.

Abstract

High endothelial venules (HEV) in lymphoid organs are specialized to facilitate the passage of lymphocytes into lymphoid parenchyma. This is accomplished by a ligand-receptor system on the endothelium and lymphocytes, which differs between lymph nodes and Peyer's patch. Experiments discussed in this paper show that other non-HEV-derived endothelial cells can acquire the characteristics of HEV and that HEV may differentiate under influences from their local micro-environments.

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