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Review
. 2021 Oct-Dec;14(4):507-515.
doi: 10.4103/apc.apc_30_21. Epub 2022 Mar 25.

Necrotizing enterocolitis and congenital heart disease

Hadi Kashif  1 , Eyad Abuelgasim  2 , Nafisa Hussain  3 , Jessica Luyt  4 , Amer Harky  5   6
Affiliations
Review

Necrotizing enterocolitis and congenital heart disease

Hadi Kashif et al. Ann Pediatr Cardiol. 2021 Oct-Dec.

Abstract

Necrotizing enterocolitis (NEC) remains a prominent surgical emergency among infant population, associated with a significant mortality, as well as various subsequent morbidities. Congenital heart disease (CHD) has an increased associated incidence with NEC in infant population. Recent research has provided insight into the pathophysiology of NEC in patients with CHD and how this differs from those without CHD. The deviation from normal circulatory physiology has a suggested association in the pathophysiology of NEC in CHD, which may have implications for the risk factors of NEC in infants with CHD, the effect on outcomes of NEC, and whether alternative approaches to management may need to be considered in comparison to classical NEC. This review aims to highlight studies that provide insight and awareness into the relationship between NEC and CHD, in order that clinicians may direct themselves more clearly toward optimal management for infants in this category.

Keywords: Bowel surgery; interventions; outcomes; pediatrics.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Pathophysiology of necrotizing enterocolitis in patients with congenital heart disease
Figure 2
Figure 2
Risk factors for necrotizing enterocolitis in patients with congenital heart disease
See this image and copyright information in PMC

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