Fitz-Hugh-Curtis Syndrome Presenting as Perihepatic and Subcapsular Enhancement on MRI
- PMID: 35528764
- PMCID: PMC9035961
- DOI: 10.1159/000523699
Fitz-Hugh-Curtis Syndrome Presenting as Perihepatic and Subcapsular Enhancement on MRI
Abstract
Fitz-Hugh-Curtis syndrome (FHCS) is a rare complication of pelvic inflammatory disease and its MRI findings remain poorly described. A 34-year-old woman was raced to our hospital with slight fever and severe right upper quadrant pain. Gadoxetic acid-enhanced magnetic resonance imaging revealed high-intensity regions in the surface and subcapsule of the right liver on T2-weighted imaging and on diffusion-weighted imaging. A definitive diagnosis of FHCS was confirmed based on high titers of serum IgA and IgG antibodies to Chlamydia trachomatis. She was treated with oral azithromycin and discharged 6 days after admission with improvement of her symptoms. To our knowledge, this report represents a valuable addition to the FHCS literature describing MRI findings in the early stage of FHCS onset.
Keywords: Chlamydia trachomatis; Fitz-Hugh-Curtis syndrome; MRI.
Copyright © 2022 by S. Karger AG, Basel.
Conflict of interest statement
The authors have no conflicts of interest to disclose in association with this study.
Figures


Similar articles
-
Fitz-Hugh-Curtis syndrome in a man positive for Chlamydia trachomatis.Clin J Gastroenterol. 2018 Aug;11(4):338-342. doi: 10.1007/s12328-018-0829-5. Epub 2018 Feb 7. Clin J Gastroenterol. 2018. PMID: 29417387 Review.
-
Fitz-Hugh-Curtis syndrome resulting in nutmeg liver on computed tomography.Radiol Case Rep. 2019 May 24;14(8):930-933. doi: 10.1016/j.radcr.2019.04.008. eCollection 2019 Aug. Radiol Case Rep. 2019. PMID: 31193761 Free PMC article.
-
Chlamydia trachomatis-Induced Fitz-Hugh-Curtis Syndrome Presenting as Inspiratory Dyspnea.Cureus. 2020 Jun 11;12(6):e8566. doi: 10.7759/cureus.8566. Cureus. 2020. PMID: 32670702 Free PMC article.
-
Positive Murphy's Sign of Fitz-Hugh-Curtis Syndrome.Cureus. 2025 Feb 4;17(2):e78521. doi: 10.7759/cureus.78521. eCollection 2025 Feb. Cureus. 2025. PMID: 40062118 Free PMC article.
-
Fitz-Hugh-Curtis syndrome: A cause of right upper quadrant abdominal pain.Med Clin (Barc). 2020 Jun 12;154(11):447-452. doi: 10.1016/j.medcli.2020.01.022. Epub 2020 Mar 4. Med Clin (Barc). 2020. PMID: 32145988 Review. English, Spanish.
References
-
- Curtis AH. A cause of adhesions in the right upper quadrant. JAMA. 1930;94((16)):1221–2.
-
- Fitz-Hugh T., Jr Acute gonococcic peritonitis of the right upper quadrant in women. JAMA. 1934;102((25)):2094–6.
-
- Wølner-Hanssen P, Weström L, Mårdh PA. Perihepatitis and chlamydial salpingitis. Lancet. 1980;315:901–4. - PubMed
-
- Watanabe M, Tanaka S, Ono M, Hamamoto S, Niigaki M, Uchida Y, et al. Laparoscopic observations of hepatic capsular abnormalities: non-postoperative adhesions and hepatic capsular thicking. Gastrointestinal Endosc. 1999;50:664–6. - PubMed
-
- Tanitame K, Tanitame N, Okano Y. Fitz-Hugh-Curtis syndrome. Clin Gastroenterol Hepatol. 2020;18:A26. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Miscellaneous