Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022:16:100419.
doi: 10.1016/j.ijans.2022.100419. Epub 2022 Apr 30.

Incidence and predictors of mortality among COVID-19 patients admitted to treatment centers in North West Ethiopia; A retrospective cohort study, 2021

Belayneh Mengist  1 , Zelalem Animut  2 , Tadesse Tolossa  3
Affiliations

Incidence and predictors of mortality among COVID-19 patients admitted to treatment centers in North West Ethiopia; A retrospective cohort study, 2021

Belayneh Mengist et al. Int J Afr Nurs Sci. 2022.

Abstract

Background: Currently, coronavirus disease 2019 (COVID-19) is the leading cause of death and the rate of mortality is rapidly increasing over time. There is a paucity of information regarding the incidence and predictors of mortality among COVID-19 patients from low-income countries, particularly in Ethiopia.

Objective: To assess incidence and predictors of mortality among COVID-19 patients admitted to treatment centers in North West Ethiopia.

Methods: An institution-based retrospective cohort study was conducted among 552 laboratory-confirmed COVID-19 cases at Debre Markos University and Tibebe Ghion Hospital COVID-19 treatment centers in North West Ethiopia from March 2020 to March 2021. Data were collected from patients' medical records using a structured data extraction tool. Cox-proportional hazards regression models was fitted to identify significant predictors of mortality.

Result: The overall mortality rate of COVID-19 was 4.7, (95 % CI: 3.3-6.8) per 1000 person day observations. Older age (AHR: 4.9; 95% CI: 1.8, 13.5), rural residence (AHR: 0.18; 95% CI: 0.05, 0.64), presence of hypertension (AHR: 3.04; 95% CI: 1.18, 7.8), presence of diabetes mellitus (AHR: 8.1; 95% CI: 2.9, 22.4) and cardiovascular disease (AHR: 5.2; 95% CI: (1.69, 16.2) were significantly associated with mortality.

Conclusions: The rate of mortality among hospitalized COVID-19 patients in this study was low. COVID-19 patients from urban residences, older patients, and patients with comorbidity have a high risk of death. These high risk groups should be prioritized for COVID-19 vaccinations, and early screening and appropriate intervention should be established on presentation to health facility.

Keywords: COVID-19, Coronavirus Disease 2019; Coronavirus; DMU, Debre Markos University; Ethiopia; ICU, Intensive Care Unit; Mortality; RT-PCR, Real-Time Reverse Transcriptase-Polymerase Chain Reaction; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; Survival analysis; TGH, Tibebe Ghion Hospital WHO: World Health Organization.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Kaplan-Meier survival curve estimating the overall survival probability of COVID-19 patients in North West Ethiopia.
Fig. 2
Fig. 2
Kaplan-Meier survival curve estimating the survival probability of COVID-19 patients by age in North West Ethiopia.
Fig. 3
Fig. 3
Kaplan-Meier survival curve estimating the survival probability of COVID-19 patients by sex in North West Ethiopia.
Fig. 4
Fig. 4
Kaplan-Meier survival curve estimating the survival probability of COVID-19 patients by co-morbidity in North West Ethiopia.
Fig. 5
Fig. 5
Cox-Snell residual graph showing the overall model goodness of fit.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Abate S.M., Checkol Y.A., Mantefardo B. Global prevalence and determinants of mortality among patients with COVID-19: A systematic review and meta-analysis. Annals of Medicine and Surgery. 2021;102204 - PMC - PubMed
    1. Abraha H.E., Gessesse Z., Gebrecherkos T., et al. Clinical features and risk factors associated with morbidity and mortality among patients with COVID-19 in northern Ethiopia. International Journal of Infectious Diseases. 2021;105:776–783. doi: 10.1016/j.ijid.2021.03.037. - DOI - PMC - PubMed
    1. Acharya D., Lee K., Lee D.S., Lee Y.S., Moon S.-S. Paper presented at the Healthcare. 2020. Mortality Rate and Predictors of Mortality in Hospitalized COVID-19 Patients with Diabetes. - PMC - PubMed
    1. Albitar O., Ballouze R., Ooi J.P., Ghadzi S.M.S. Risk factors for mortality among COVID-19 patients. Diabetes research and clinical practice. 2020;166 - PMC - PubMed
    1. Bamgboye E.L., Omiye J.A., Afolaranmi O.J., Davids M.R., Tannor E.K., Wadee S., et al. COVID-19 pandemic: Is Africa different? Journal of the National Medical Association. 2021;113(3):324–335. - PMC - PubMed