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. 2022 May:77:103676.
doi: 10.1016/j.amsu.2022.103676. Epub 2022 Apr 30.

Co-infection of SARS-CoV-2 with other viral respiratory pathogens in Yogyakarta, Indonesia: A cross-sectional study

Eggi Arguni  1 , Endah Supriyati  2   3 , Mohamad Saifudin Hakim  4 , Edwin Widyanto Daniwijaya  4 , Firdian Makrufardi  1 , Ayu Rahayu  2   3 , Anwar Rovik  2   3 , Utari Saraswati  2   3 , Farida Nur Oktoviani  4 , Nenes Prastiwi  4 , Titik Nuryastuti  4 , Tri Wibawa  4 , Sofia Mubarika Haryana  5
Affiliations

Co-infection of SARS-CoV-2 with other viral respiratory pathogens in Yogyakarta, Indonesia: A cross-sectional study

Eggi Arguni et al. Ann Med Surg (Lond). 2022 May.

Abstract

Background: Growing evidence shows that viral co-infection is found repeatedly in patients with Coronavirus Disease-2019 (COVID-19). This is the first report of SARS-CoV-2 co-infection with viral respiratory pathogens in Indonesia.

Methods: Over a one month period of April to May 2020, SARS-CoV-2 positive nasopharyngeal swabs in our COVID-19 referral laboratory in Yogyakarta, Indonesia, were tested for viral respiratory pathogens by real-time, reverse transcription polymerase chain reaction (RT-PCR). Proportion of co-infection reported in percentage.

Results: Fifty-nine samples were positive for other viral respiratory pathogens among a total of 125 samples. Influenza A virus was detected in 32 samples, Influenza B in 16 samples, Human metapneumovirus in 1 sample, and adenovirus in 10 samples. We did not detect any co-infection with respiratory syncytial virus. Nine (7.2%) patients had co-infection with more than two viruses.

Conclusion: Viral co-infection with SARS-CoV-2 is common. These results will provide a helpful reference for diagnosis and clinical treatment of patients with COVID-19.

Keywords: COVID-19; Co-infection; Coronavirus; SARS-CoV-2; Viral respiratory pathogens.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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