Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Aug;42(9):2110-2116.
doi: 10.1111/liv.15288. Epub 2022 May 16.

Liver transplantation in patients with liver failure: Twenty years of experience from China

Sunbin Ling  1   2   3 , Guangjiang Jiang  1   2   3 , Qingyang Que  1   2   3 , Shengjun Xu  1   2   3 , Junli Chen  4 , Xiao Xu  1   2   3   4   5
Affiliations
Review

Liver transplantation in patients with liver failure: Twenty years of experience from China

Sunbin Ling et al. Liver Int. 2022 Aug.

Abstract

Liver transplantation (LT) is the only effective method of treating end-stage liver disease, such as various types of liver failure. China has the largest number of patients with hepatitis B virus-related disease, which is also the main cause of liver failure. From the first LT performed in 1977, and especially over the past two decades, LT has experienced rapid development as a result of continuous research and innovation in China. China performs the second-highest number of LTs every year worldwide, and the quality of LT continues to improve. Starting January 1, 2015, all donor's livers have been from deceased donors and familial donors. Thus, China entered into a new era of LT. However, LT is still a challenging procedure in China. In this review, we introduced the brief history of LT in China, the epidemiology, aetiology and clinical outcomes of LT for liver failure in China and summarized the experience of LT from Chinese LT surgeons and scholars. The future perspectives of LT were also discussed, and it is expected that China's LT research could be further integrated elsewhere in the world.

Keywords: China; liver failure; liver transplantation.

PubMed Disclaimer

Comment in

References

REFERENCES

    1. Organization committee of 13th Asia-Pacific congress of clinical M, infection. 13th Asia-Pacific congress of clinical microbiology and infection consensus guidelines for diagnosis and treatment of liver failure. Hepatobiliary Pancreat Dis Int. 2013;12(4):346-354.
    1. Martin P, DiMartini A, Feng S, Brown R Jr, Fallon M. Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Hepatology. 2014;59(3):1144-1165.
    1. Xu X, Chen J, Wei Q, et al. Clinical practice guidelines on liver transplantation for hepatocellular carcinoma in China (2018 edition). Hepatobiliary Pancreat Dis Int. 2019;18(4):307-312.
    1. Shen T, Zhuang L, Sun XD, et al. Expert consensus on management of metabolic disease in Chinese liver transplant recipients. World J Gastroenterol. 2020;26(27):3851-3864.
    1. Transplant Experts of the National Organ D, Transplantation C, Officers of National H et al. The new era of organ transplantation in China. Chin Med J (Engl). 2016;129(16):1891-1893.

Publication types

LinkOut - more resources