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Case Reports
. 2025 Feb;104(2):NP68-NP71.
doi: 10.1177/01455613221101087. Epub 2022 May 9.

Inflammatory myofibroblastic tumour of the larynx: report of a case

Andrea Colizza  1 , Piero Giuseppe Meliante  1 , Samantha Donsante  2 , Mara Riminucci  2 , Antonio Greco  1 , Marco De Vincentiis  1 , Alessandro Corsi  2
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Free article
Case Reports

Inflammatory myofibroblastic tumour of the larynx: report of a case

Andrea Colizza et al. Ear Nose Throat J. 2025 Feb.
Free article

Abstract

Only 0.3-1% of laryngeal cancer are non-squamous cell neoplasms. Of these, a rare entity is inflammatory myofibroblastic tumour (IMT), in which anaplastic lymphoma kinase-1 (ALK-1) is frequently expressed. Just 50 cases of IMT have been reported. Therefore, many otolaryngologists may be unfamiliar with this type of tumour and be prone to its over- or undertreatment.We report a case of ALK-1-negative IMT treated with transoral endoscopic excision and disease-free 6 months after surgery.

Keywords: Larynx; inflammatory myofibroblastic tumour; laryngeal neoplasms; transoral surgery.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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