Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug;45(2):235-245.
doi: 10.1016/j.rbmo.2022.02.026. Epub 2022 Mar 12.

Assisted reproductive technologies in Latin America: the Latin American Registry, 2019

Fernando Zegers-Hochschild  1 , Javier A Crosby  2 , Carolina Musri  2 , Maria do Carmo Borges de Souza  3 , A Gustavo Martinez  4 , Adelino Amaral Silva  5 , José María Mojarra  6 , Diego Masoli  2 , Natalia Posada  7 ; Latin American Network of Assisted Reproduction  8
Affiliations

Assisted reproductive technologies in Latin America: the Latin American Registry, 2019

Fernando Zegers-Hochschild et al. Reprod Biomed Online. 2022 Aug.

Abstract

Research question: What was the utilization, effectiveness and safety of assisted reproductive technology (ART) in Latin America during 2019?

Design: This was a retrospective collection of multinational data on ART performed at 196 institutions from 15 countries.

Results: A total of 106,918 initiated cycles, 18,133 deliveries and 21,096 births were reported. ART utilization was 24-558 cycles per million inhabitants. Women aged ≥40 years represented 32.9% of fresh IVF and intracytoplasmic sperm injection (ICSI) cycles. After removing freeze-all cycles, the delivery rate per oocyte retrieval was 17.3% for ICSI and 19.5% for IVF. Overall, single-embryo transfer (SET) represented 36.2% of fresh transfers, with a 19.5% delivery rate per transfer, increasing to 30.7% for elective SET and 32.7% for blastocyst elective SET (eSET). The delivery rate for double-embryo transfers (DET) was 27.8%, increasing to 37.1% after elective DET. This 6.4% increment in deliveries between eSET and elective DET resulted in a 12-fold increase in twin births. Furthermore, overall perinatal mortality was more than two-fold higher for twin compared with singleton deliveries. The delivery rate for frozen-thawed SET reached 28.1%, most being blastocyst transfers. Of all births, 72.3% were singletons, 26.4% twins and 1.3% triplets and higher multiples. Preterm deliveries reached 14.3% for singletons and 58.1% for twins. Perinatal mortality was 7.4‰ in singletons, 17.2‰ for twins and 62.9‰ for triplets or higher.

Conclusions: The number of initiated cycles has slowly increased in countries with laws or regulations facilitating access. FET cycles predominate and blastocyst SET are also increasing. The data show that, especially in young women and oocyte recipients, when there is more than one blastocyst for transfer, eSET should be the rule.

Keywords: ART utilization; Assisted reproductive technology; Efficacy; Latin American Registry; Perinatal outcome.

PubMed Disclaimer

LinkOut - more resources