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Review
. 2022 May;55(3):339-346.
doi: 10.5946/ce.2021.249. Epub 2022 Apr 28.

Endoscopic clipping in non-variceal upper gastrointestinal bleeding treatment

Giuseppe Galloro  1 , Angelo Zullo  2 , Gaetano Luglio  1 , Alessia Chini  1 , Donato Alessandro Telesca  3 , Rosa Maione  1 , Matteo Pollastro  1 , Giovanni Domenico De Palma  1 , Raffaele Manta  4
Affiliations
Review

Endoscopic clipping in non-variceal upper gastrointestinal bleeding treatment

Giuseppe Galloro et al. Clin Endosc. 2022 May.

Abstract

Since the earliest reports, advanced clipping systems have been developed, and it is possible to choose among many models with different structural and technical features. The main drawback of through-the-scope clips is their small size, which allows the compression of limited amounts of tissue needed for large-size vessel treatment. Therefore, the over-the-scope clip system was realized, allowing a larger and stronger mechanical compression of large tissue areas, with excellent results in achieving a definitive hemostasis in difficult cases. Many studies have analyzed the indications and efficacy of two-pronged endoclips and have shown good results for initial and permanent hemostasis. The aim of this review was to provide updated information on indications, positioning techniques, and results of clip application for endoscopic treatment of upper gastrointestinal non-variceal bleeding lesions.

Keywords: Clipping; Digestive endoscopy; Endoclips; Gastrointestinal bleeding; Over-the-scope clip.

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Conflict of interest statement

Conflicts of Interest

The authors have no potential conflicts of interest.

Figures

Fig. 1.
Fig. 1.
Physical and functional features of through-the-scope (TTS) clips. +++, best performance; ++, good performance; +, medium perfor­mance.
Fig. 2.
Fig. 2.
Main features of the over-the-scope clip (OTSC).
See this image and copyright information in PMC

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