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Review
. 2022 Sep;11(3):100864.
doi: 10.1016/j.imr.2022.100864. Epub 2022 Apr 6.

Effectiveness and safety of acupuncture for angina pectoris: An overview of systematic reviews

Wen-Chuan Qi  1   2 , Hong-Juan Fu  1 , Rui-Rui Sun  1   2 , Xiang Li  1   2 , Ding-Jun Cai  1   2 , Chao Wang  1   3 , Fan-Rong Liang  1   2
Affiliations
Review

Effectiveness and safety of acupuncture for angina pectoris: An overview of systematic reviews

Wen-Chuan Qi et al. Integr Med Res. 2022 Sep.

Abstract

Background: The number of systematic reviews meta-analyses (SRs/MAs) on the effectiveness of acupuncture for angina pectoris (AP) is increasing. Due to the inconsistent conclusions and unknown quality of these SRs/MAs, this overview aimed to systematically evaluate and synthesize the existing SRs/MAs, attempting to provide more reliable evidence for the effectiveness and safety of acupuncture in the treatment of AP.

Methods: SRs/MAs were searched via eight databases from inception to March 14, 2022. The risk of bias was evaluated using the Risk of Bias in Systematic reviews (ROBIS) tool. The quality of the methodology, reporting, and evidence were assessed by the Assess Systematic Reviews 2 (AMSTAR-2), the Preferred Reporting Item for Systematic Review and Meta-analysis for Acupuncture (PRISMA-A), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, respectively.

Results: Sixteen SRs/MAs were included and fifteen SRs/MAs were considered being of critically low quality according to AMSTAR-2. Only three SRs/MAs were rated at low risk of bias. No study reported all the items listed in the PRISMA-A checklist. No high-quality evidence with GRADE assessment was found. With the low-quality evidence, acupuncture combined with other interventions was superior to monotherapy (medications or Chinese medicine) in the angina symptom and electrocardiogram recovery. No adverse effects owing to acupuncture were reported.

Conclusions: Owing to the lack of high-quality evidence provided by the current SRs/MAs, the effectiveness of acupuncture for AP still warrants further proof. Further researches with more critical design and methodology are needed for providing more convincing evidence.

Registration: This review was registered at PROSPERO (www.crd.york.ac.uk/prospero/): CRD42021219367.

Keywords: Acupuncture; Angina pectoris; Overview; Systematic reviews.

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Figures

Fig. 1
Fig. 1
Flowchart of the selection process of included SRs/MAs.
See this image and copyright information in PMC

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References

    1. Alam K., Mahal A. The economic burden of angina on households in South Asia. BMC Public Health. 2014;14:179. - PMC - PubMed
    1. Strong K., Mathers C., Leeder S., Beaglehole R. Preventing chronic diseases: how many lives can we save? Lancet. 2005;366(9496):1578–1582. - PubMed
    1. Benjamin E.J., Blaha M.J., Chiuve S.E., Cushman M., Das S.R., Deo R., et al. Heart disease and stroke statistics-2017 update: a report from the American heart association. Circulation. 2017;135(10):e146–e603. - PMC - PubMed
    1. Ohman E.M. Clinical practice. Chronic stable angina. N Engl J Med. 2016;374(12):1167–1176. - PubMed
    1. Henderson R.A., O’Flynn N., Group G.D. Management of stable angina: summary of NICE guidance. Heart. 2012;98(6):500–507. - PubMed

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