Evidence that the sigma 1 protein of reovirus serotype 3 is a multimer
- PMID: 3553613
- PMCID: PMC254187
- DOI: 10.1128/JVI.61.6.1834-1841.1987
Evidence that the sigma 1 protein of reovirus serotype 3 is a multimer
Abstract
In this report, we study the reovirus serotype 3 (strain Dearing) sigma 1 protein obtained from various sources: from Escherichia coli expressing sigma 1 protein, from reovirus-infected mouse L cells, and from purified reovirions. We demonstrate that the sigma 1 protein is a multimer in its undisrupted form and present biochemical evidence suggesting that the multimer is made up of four sigma 1 subunits.
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