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Review
. 2023 Jan 1;45(1):e135-e138.
doi: 10.1097/MPH.0000000000002474. Epub 2022 May 3.

Primitive Myxoid Mesenchymal Tumor of Infancy With Fatal Hemorrhage In Utero: A Case Report and Literature Review

Mitsuhiro Haga  1 , Yukiko Motojima  1 , Wataru Masuda  2 , Takashi Fujino  3   4 , Jun-Ichi Tamaru  2 , Takumi Nakamura  5 , Soichi Oya  5 , Takayuki Amikura  6 , Masahiko Higashino  6 , Masayo Kanai  1 , Koichi Moriwaki  1
Affiliations
Review

Primitive Myxoid Mesenchymal Tumor of Infancy With Fatal Hemorrhage In Utero: A Case Report and Literature Review

Mitsuhiro Haga et al. J Pediatr Hematol Oncol. .

Abstract

Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a rare soft tissue sarcoma in childhood. We present the case of a newborn male who experienced a severe hemorrhage in utero from the tumor on the scalp. He died at the age of 24 hours owing to hemorrhagic shock. The tumor was posthumously diagnosed as PMMTI. A literature search indicated that cases of severe hemorrhage from soft tissue sarcomas in utero or at birth are limited to infantile fibrosarcoma. This is the first case of PMMTI with massive hemorrhage. Clinicians must be aware of hemorrhagic complications of PMMTI.

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Conflict of interest statement

The authors declare no conflict of interest.

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