doi: 10.1038/326846a0.
Structure of the repressor-operator complex of bacteriophage 434
- PMID: 3553959
- DOI: 10.1038/326846a0
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Structure of the repressor-operator complex of bacteriophage 434
Nature.
1987.
Abstract
The crystal structure of a specific complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator DNA shows interactions that determine sequence-dependent affinity. The repressor recognizes its operators by its complementarity to a particular DNA conformation as well as by direct interaction with base pairs in the major groove.
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