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Review
. 2022 Dec;54(1):1350-1356.
doi: 10.1080/07853890.2022.2071459.

The role of miRNA-210 in pre-eclampsia development

Ilona Jaszczuk  1 , Dorota Koczkodaj  1 , Adrianna Kondracka  2 , Anna Kwaśniewska  2 , Izabela Winkler  3 , Agata Filip  1
Affiliations
Review

The role of miRNA-210 in pre-eclampsia development

Ilona Jaszczuk et al. Ann Med. 2022 Dec.

Abstract

MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic acids) that play important roles in many vital processes through their impact on gene expression. One such miRNA, miR210, represents a hypoxia-induced cellular miRNA group that hold a variety of functions. This review article highlights the importance of miR-210 in the development of pre-eclampsia.KEY MESSAGEmiR-210 is a promising biomarker for monitoring pregnancy with pre-eclampsia. Overexpression of miR-210 had a negative impact on the process of cell migration and trophoblast invasion.

Keywords: hypoxia; miR-210; pre-eclampsia.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
The impact of incorrect trophoblast implantation and vascular complications on pre-eclampsia development.
Figure 2.
Figure 2.
Regulation of expression of selected genes by miR-210 under hypoxic condition.
See this image and copyright information in PMC

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