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Comment
. 2022 May 10;55(5):821-823.
doi: 10.1016/j.immuni.2022.04.008.

InFlamiN' the brain in Alzheimer's disease

Jonas J Neher  1
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InFlamiN' the brain in Alzheimer's disease

Jonas J Neher. Immunity. .
Free article

Abstract

Although consistently implicated, the exact role of interferon (IFN) signaling in Alzheimer's disease remains largely unexplored. Roy et al. now demonstrate that type I IFNs may drive cognitive dysfunction through acting not only on microglia but, surprisingly, also on neurons.

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Conflict of interest statement

Declaration of interests The author declares no competing interests.

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