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Review
. 2022 Apr 29:28:1747.
doi: 10.4102/sajpsychiatry.v28i0.1747. eCollection 2022.

Early deviant behaviour as a dimension trait and endophenotype in schizophrenia

Johannes L Roos  1   2 , Carla Kotzé  1   2
Affiliations
Review

Early deviant behaviour as a dimension trait and endophenotype in schizophrenia

Johannes L Roos et al. S Afr J Psychiatr. .

Abstract

Background: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a more personalised approach to patients.

Aim: To discuss how early deviant behaviour (EDB) may be seen as a possible continuous symptom dimension trait and endophenotype in schizophrenia.

Methods: Conducting a commentary review by highlighting some important findings from available literature.

Results: Findings regarding EDB in schizophrenia in a South African genetic sample point towards EDB as a progressive subtype of schizophrenia, with very early onset of illness (even prior to the psychotic symptomatology) and a genetic form of illness.

Conclusion: Valuable information can be gained by enquiring into EDB and viewing it as a continuous symptom dimension trait and endophenotype during the psychiatric diagnostic interview.

Keywords: continuous symptom dimension; deviant behaviour; early onset; endophenotype; schizophrenia.

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Conflict of interest statement

The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this commentary review.

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