Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 May 5:16:1427-1437.
doi: 10.2147/OPTH.S362307. eCollection 2022.

Changes in Noncontact Meibography and Noninvasive Tear Break-Up Time Test with Contact Lenses Usage

Reham Fattoh  1 , Amr Mounir  2 , Mohamed Anbar  2 , Osama Ali Mohammed  2
Affiliations

Changes in Noncontact Meibography and Noninvasive Tear Break-Up Time Test with Contact Lenses Usage

Reham Fattoh et al. Clin Ophthalmol. .

Abstract

Purpose: The study aimed to determine changes detected by noncontact meibography and noninvasive break-up time test (NIBUT) in individuals with regular use of soft contact lenses and compare these findings with irregular soft contact lenses wearers who not compliant with them and non-wearers control group.

Patients and methods: A prospective nonrandomized case-control study in which individuals were recruited and distributed into three groups: Group A (regular contact lens wearers), group B (irregular contact lens wearers), and group C (non-wearers). Ocular Surface Disease Index (OSDI) was obtained. Noncontact meibography and noninvasive tear break-up time were measured without lenses on using Sirius® Scheimpflug Camera.

Results: One hundred sixty-six eyes of 83 individuals were included; 36 eyes in group A, 50 eyes in group B, and 80 eyes in group C. The mean total meiboscore was 1.99, 1.61, and 1.28, respectively. The mean meibograde was 3.03, 2.86, and 1.99, respectively. Noninvasive break-up time (NIF-BUT) was 8.42, 11.76, and 13.57 seconds, respectively.

Conclusion: There is a difference in OSDI score, meibomian score, and break-up time between different study groups. The study results show that there are trends in lens wearers and non-lens wearers. This is useful for the field to understand the differences between lens wearers and non-lens wearers.

Keywords: noncontact meibography; noninvasive break-up time; soft contact lenses.

PubMed Disclaimer

Conflict of interest statement

The authors have no financial or proprietary interest in the product, method, or material described herein. The authors declare that they have no conflicts of interest for this work.

Figures

Figure 1
Figure 1
Red area describes the area of the lower lid examined by meibography while green area shows dilatation and tortuosity of the meibomian glands Meiboscore grade II.
Figure 2
Figure 2
Red area describes the area of the upper lid examined by meibography while green area shows the meibomian glands loss, distortion, and tortuosity.
Figure 3
Figure 3
(A) Mild affected and noninvasive break-up time test (NIF-BUT) and noninvasive average break-up time test (NIAvg-BUT) (green area shows normal break-up time of the tear film while red and orange color shows abnormal break-up time. (B) Markedly affected NIF-BUT and NIAvg-BUT
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II epidemiology report. Ocul Surf. 2017;15(3):334–365. doi:10.1016/j.jtos.2017.05.003 - DOI - PubMed
    1. Uchino M, Yokoi N, Uchino Y, et al. Prevalence of dry eye disease and its risk factors in visual display terminal users: the Osaka study. Am J Ophthalmol. 2013;156(4):759–766. doi:10.1016/j.ajo.2013.05.040 - DOI - PubMed
    1. Uchino M, Uchino Y, Dogru M, et al. Dry eye disease and work productivity loss in visual display users: the Osaka study. Am J Ophthalmol. 2014;157(2):294–300. doi:10.1016/j.ajo.2013.10.014 - DOI - PubMed
    1. Kim YH, Nguyen T, Lin MC, et al. Protection against corneal hyperosmolarity with soft-contact-lens wear [published online ahead of print, 2021 Sep 29]. Prog Retin Eye Res. 2021;4:101012. - PubMed
    1. Nichols JJ, Sinnott LT. Tear film, contact lens, and patient related factors associated with contact lens-related dry eye. Invest Ophthalmol Vis Sci. 2006;47:1319–1328. doi:10.1167/iovs.05-1392 - DOI - PubMed