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. 2022 May 4:13:155-163.
doi: 10.2147/PHMT.S358250. eCollection 2022.

Characterization of the Difficult Peripheral IV in the Perioperative Setting: A Prospective, Observational Study of Intravenous Access for Pediatric Patients Undergoing Anesthesia

Affiliations

Characterization of the Difficult Peripheral IV in the Perioperative Setting: A Prospective, Observational Study of Intravenous Access for Pediatric Patients Undergoing Anesthesia

Grant Heydinger et al. Pediatric Health Med Ther. .

Abstract

Background: Various criteria exist for defining difficult intravenous access (DIVA) in infants and children. The current study evaluated the factors associated with DIVA in a prospective cohort of over 1000 infants and children presenting for anesthetic care.

Methods: This was a prospective, observational study of patients aged 0 to 18 years undergoing elective surgical or radiologic procedures under general anesthesia. Prior to the initial attempt at peripheral intravenous (PIV) cannulation, the anticipated difficulty of PIV catheter placement was determined by the provider using a visual analogue scale (VAS) from 1 to 10. The number of attempts was recorded as well as the time required to achieve PIV access. DIVA was defined as requiring three or more attempts. After successful cannulation, the actual difficulty of the PIV placement was assessed by the provider and recorded using the same VAS. Patient characteristics, including age, race, body mass index (BMI), American Society of Anesthesiologists (ASA) physical classification, and history of difficult PIV placement, were evaluated as covariates.

Results: In our cohort of 1002 pediatric patients, 78% of patients were successfully cannulated in a single attempt and 91% of patients were successfully cannulated in two or fewer attempts. Factors associated with requiring three or more PIV attempts included younger age (OR 8.73; 95% CI: 3.38, 22.6 for age <1 year and OR 4.93; 95% CI: 2.05, 11.8 for age 1-3 years), higher ASA physical classification (OR 1.95; 95% CI: 1.10, 3.46 for ASA II), and prior history of difficult PIV placement (OR 3.46; 95% CI: 1.70, 7.08). BMI, racial category or gender were not independent predictors of DIVA.

Conclusion: We found that approximately 9% of patients required three or more attempts at IV placement in the operating room. Patients that required multiple PIV attempts were more likely to be younger, have a higher ASA classification or a history of difficult PIV placement.

Keywords: intravenous cannulation; pediatric anesthesiology; peripheral intravenous catheter; vascular access.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Risk factors with odds ratios for 2 or more (black circles) and 3 or more attempts (black diamonds).

References

    1. Hartman JH, Baker J, Bena JF, Morrison SL, Albert NM. Pediatric vascular access peripheral IV algorithm success rate. J Pediatr Nurs. 2018;39:1–6. doi:10.1016/j.pedn.2017.12.002 - DOI - PubMed
    1. Schults J, Rickard C, Kleidon T, Paterson R, Macfarlane F, Ullman A. Difficult peripheral venous access in children: an international survey and critical appraisal of assessment tools and escalation pathways. J Nurs Scholarsh. 2019;51(5):537–546. doi:10.1111/jnu.12505 - DOI - PubMed
    1. Cuper NJ, de Graaff JC, van Dijk ATH, Verdaasdonk RM, van der Werff DBM, Kalkman CJ. Predictive factors for difficult intravenous cannulation in pediatric patients at a tertiary pediatric hospital. Paediatr Anaesth. 2012;22(3):223–229. doi:10.1111/j.1460-9592.2011.03685.x - DOI - PubMed
    1. Young KD. Pediatric procedural pain. Ann Emerg Med. 2005;45(2):160–171. doi:10.1016/j.annemergmed.2004.09.019 - DOI - PubMed
    1. Armenteros-Yeguas V, Gárate-Echenique L, Tomás-López MA, et al. Prevalence of difficult venous access and associated risk factors in highly complex hospitalised patients. J Clin Nurs. 2017;26(23–24):4267–4275. doi:10.1111/jocn.13750 - DOI - PMC - PubMed