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Review
. 2022 Jun;38(6):509-516.
doi: 10.1002/kjm2.12554. Epub 2022 May 12.

A review of the phytochemical and pharmacological properties of Amauroderma rugosum

Cheng-Wen Zheng  1 , Timothy Man-Yau Cheung  2 , George Pak-Heng Leung  1
Affiliations
Review

A review of the phytochemical and pharmacological properties of Amauroderma rugosum

Cheng-Wen Zheng et al. Kaohsiung J Med Sci. 2022 Jun.

Abstract

Amauroderma rugosum (AR) is a basidiomycete in the Ganodermataceae family that has been used traditionally to prevent epileptic attacks and constant crying in babies. However, AR has not been widely studied scientifically. In this review, we summarize the phytochemical components and pharmacological properties of AR that have been reported in the literature. Chemical analyses have revealed that the components of AR include sterols, flavonoids, fatty acids and esters, aromatic acids and esters, phenols, polysaccharides, and triterpenes. Pharmacological properties of AR include antioxidant, anti-inflammatory, neuroprotective, anti-cancer, anti-hyperlipidemic, anti-epileptic, and antibacterial effects. These findings suggest that AR and its bioactive ingredients have potential therapeutic applications, particularly for age-related diseases.

Keywords: anti-cancer; anti-inflammatory; antioxidant; pharmacology; phytochemicals.

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Conflict of interest statement

All authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
The fruiting body of Amauroderma rugosum
See this image and copyright information in PMC

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