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Clinical Trial
. 2022 Aug;198(8):755-758.
doi: 10.1007/s00066-022-01948-9. Epub 2022 May 13.

[Phase II study on treatment de-escalation in HPV-associated oropharyngeal cancer]

[Article in German]
Robert Michael Hermann  1 , Hans Christiansen  2
Affiliations
Clinical Trial

[Phase II study on treatment de-escalation in HPV-associated oropharyngeal cancer]

[Article in German]
Robert Michael Hermann et al. Strahlenther Onkol. 2022 Aug.
No abstract available

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References

    1. Tawk B, Debus J, Abdollahi A. Evolution of a paradigm switch in diagnosis and treatment of HPV-driven head and neck cancer-striking the balance between toxicity and cure. Front Pharmacol. 2022;12:753387. doi: 10.3389/fphar.2021.753387. - DOI - PMC - PubMed
    1. Nichols AC, Theurer J, Prisman E, et al. Radiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial. Lancet Oncol. 2021;20:1349–1359. doi: 10.1016/S1470-2045(19)30410-3. - DOI - PubMed
    1. Gillison ML, Trotti AM, Harris J, et al. Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. Lancet. 2019;393:40–50. doi: 10.1016/S0140-6736(18)32779-X. - DOI - PMC - PubMed
    1. Mehanna H, Robinson M, Hartley A, et al. Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial. Lancet. 2019;393:51–60. doi: 10.1016/S0140-6736(18)32752-1. - DOI - PMC - PubMed
    1. McDowell L, Magarey MJR, Rischin D. Transoral surgery and deintensified adjuvant therapy: another step in determining its role in the management of human papillomavirus oropharyngeal cancer. J Clin Oncol. 2022;40:114–117. doi: 10.1200/JCO.21.02364. - DOI - PubMed

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