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Review
. 2022 Jul;22(7):383-388.
doi: 10.1007/s11910-022-01201-x. Epub 2022 May 13.

Internal Carotid Artery Occlusion: Management

Harneel Saini  1 , Russell Cerejo  1 , Richard Williamson  2 , Konark Malhotra  3
Affiliations
Review

Internal Carotid Artery Occlusion: Management

Harneel Saini et al. Curr Neurol Neurosci Rep. 2022 Jul.

Abstract

Purpose of review: Acute internal carotid artery occlusion (ICAO) is associated with high rates of morbidity and mortality, whereas chronic ICAO can present insidiously with recurrent strokes. In this review, we discuss the medical and surgical management approaches among patients with acute, subacute, and chronic ICAO.

Recent findings: We reviewed the recent literature regarding clinical presentation of acute and chronic cases of ICAO, and discuss the current data, accepted guidelines, and prospects. Surgical, endovascular, or a combination (hybrid) revascularization has been shown to be effective in recanalization with improved functional outcomes in patients with ICAO in comparison to systemic thrombolysis or medical therapy alone. Future prospective or randomized clinical trials are warranted to elucidate the procedural superiority for revascularization of patients with ICAO.

Keywords: Internal carotid artery; Recanalization; Stroke; Vessel occlusion.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
    1. Malhotra K, Gornbein J, Saver JL. Ischemic strokes due to large-vessel occlusions contribute disproportionately to stroke-related dependence and death: a review. Front Neurol. 2017. https://doi.org/10.3389/fneur.2017.00651 . - DOI - PubMed - PMC
    1. Clagett GP, Faught WE, van Bemmelen PS, Mattos MA, Hodgson KJ, Barkmeier LD, Ramsey DE. Presentation and natural history of internal carotid artery occlusion. J Vasc Surg. 1993;18:512–24. - DOI
    1. Malhotra K, Goyal N, Tsivgoulis G. Internal carotid artery occlusion: pathophysiology, diagnosis, and management. Curr Atheroscler Rep. 2017. https://doi.org/10.1007/s11883-017-0677-7 . - DOI - PubMed
    1. Malhotra, Liebeskind. Collaterals in ischemic stroke. In: Malhotra, Konark; Liebeskind, David S. | download. https://ur.booksc.eu/book/80863057/ddc2de . Accessed 23 Sep 2021.
    1. Rubiera M, Ribo M, Delgado-Mederos R, Santamarina E, Delgado P, Montaner J, José A-S, Molina CA. Tandem internal carotid artery/middle cerebral artery occlusion. Stroke. 2006;37:2301–5. - DOI

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