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. 2022:2452:465-473.
doi: 10.1007/978-1-0716-2111-0_25.

Methods of SARS-CoV-2 Inactivation

Enyia R Anderson  1   2   3 , Tessa Prince  4 , Lance Turtle  4   5 , Grant L Hughes #  1   2   3 , Edward I Patterson #  6
Affiliations

Methods of SARS-CoV-2 Inactivation

Enyia R Anderson et al. Methods Mol Biol. 2022.

Abstract

Inactivation methods allow for hazard group 3 (HG3) pathogens to be disposed of and used safely in downstream experiments and assays to be carried out at lower containment levels. Commonly used viral inactivation methods include heat inactivation, fixation methods, ultraviolet (UV) light and detergent inactivation. Here we describe known methods used to inactivate SARS-CoV-2 for safe downstream biological assays.

Keywords: Assay; Inactivation; SARS-CoV-2; TRIzol; UV; Vero.

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References

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