The hormonal basis of ectopic pregnancy

Abstract

The endocrine origin of EP revolves around certain endocrine events that modify reproductive tract function. The reproductive tract and the embryo are highly dependent on the proper function. Changes in this environment from either external or internal origin can lead to abnormalities in implantation including EP. Based on the examples presented above, it seems that both a high estrogenic or a high progestogenic environment can contribute to an increased risk of EP. This observation stresses the importance of the proper hormonal balance rather than an absolute value of a single hormone in the normal implantation process.