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Comment
. 2022 Jul;35(7):e15580.
doi: 10.1111/dth.15580. Epub 2022 May 26.

Therapeutic targets for vaccination in polyomavirus-driven Merkel cell carcinoma

Tejas P Joshi  1 , Morgan A Farr  1 , David A Hsiou  1 , Shannon Nugent  2 , Ramie A Fathy  3 , Daniel J Lewis  4
Affiliations
Comment

Therapeutic targets for vaccination in polyomavirus-driven Merkel cell carcinoma

Tejas P Joshi et al. Dermatol Ther. 2022 Jul.
No abstract available

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References

REFERENCES

    1. Hernandez LE, Mohsin N, Yaghi M, Frech FS, Dreyfuss I, Nouri K. Merkel cell carcinoma: an updated review of pathogenesis, diagnosis, and treatment options. Dermatol Ther. 2021;29:e15292.
    1. Tabachnick-Cherny S, Pulliam T, Church C, Koelle DM, Nghiem P. Polyomavirus-driven Merkel cell carcinoma: prospects for therapeutic vaccine development. Mol Carcinog. 2020;59(7):807-821.
    1. Gehrcken L, Sauerer T, Schaft N, Dörrie J. T-cell responses in Merkel cell carcinoma: implications for improved immune checkpoint blockade and other therapeutic options. Int J Mol Sci. 2021;22(16):8679.
    1. Longino NV, Yang J, Iyer JG, et al. Human CD4+ T cells specific for Merkel cell polyomavirus localize to Merkel cell carcinomas and target a required oncogenic domain. Cancer Immunol Res. 2019;7(10):1727-1739.
    1. Jing L, Ott M, Church CD, et al. Prevalent and diverse intratumoral oncoprotein-specific CD8+ T cells within polyomavirus-driven Merkel cell carcinomas. Cancer Immunol Res. 2020;8(5):648-659.

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