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Randomized Controlled Trial
. 2022 Oct;58(4):2676-2686.
doi: 10.1111/ppc.13108. Epub 2022 May 13.

Impact of nurse-led medication adherence therapy on bipolar affective disorder: A randomized controlled trial

Affiliations
Randomized Controlled Trial

Impact of nurse-led medication adherence therapy on bipolar affective disorder: A randomized controlled trial

Shreedevi I Balikai et al. Perspect Psychiatr Care. 2022 Oct.

Abstract

Purpose: This study evaluated the impact of nurse-led medication adherence therapy (MAT) on medication adherence behavior and symptom severity of inpatients with bipolar disorder.

Method: Two arms, single-blind, randomized controlled trial on individuals with bipolar disorder was conducted at inpatient department of mental healthcare setting, India. Eighty-five participants were randomly allocated to MAT group and Treatment as usual group. Standard measures were used to assess medication adherence and symptom severity of both groups at baseline and follow-up time points.

Conclusion: MAT improved medication adherence behavior resulting in marked decrease in symptom severity of participants with bipolar disorders.

Implications for nursing practice: Psychiatric nurses can effectively implement MAT for bipolar inpatients, which improves better clinical outcomes, prevent relapse, and readmissions.

Keywords: bipolar disorder; medication adherence therapy; nurse-led.

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References

REFERENCES

    1. American Medical Association. (2020). Patient support and advocacy. Eight reasons patients don't take their medications. Retrieved August 13, 2021 from https://www.ama-assn.org/delivering-care/patient-support-advocacy/8-reas...
    1. Anbazhagan, S., Fathima, F., Agrawal, T., & Misquith, D. (2016). Psychometric properties of Morisky Medication Adherence Scale (MMAS) in known diabetic and hypertensive patients in a rural population of Kolar District, Karnataka. Indian Journal of Public Health Research and Development, 7(2), 250. https://doi.org/10.5958/0976-5506.2016.00102.9
    1. Bahredar, M. J., Asgharnejad Farid, A. A., Ghanizadeh, A., & Birashk, B. (2014). The efficacy of psycho-educational group program on medication adherence and global functioning of patients with bipolar disorder type I. International Journal of Community-Based Nursing and Midwifery, 2(1), 12-19.
    1. Bauer, M., Glenn, T., Alda, M., Bauer, R., Grof, P., Marsh, W., Monteith, S., Munoz, R., Rasgon, N., Sagduyu, K., & Whybrow, P. C. (2019). Trajectories of adherence to mood stabilizers in patients with bipolar disorder. International Journal of Bipolar Disorders, 7(19), 5283. https://doi.org/10.1186/s40345-019-0154-z
    1. Bowskill, R., Clatworthy, J., Parham, R., Rank, T., & Horne, R. (2007). Patients' perceptions of information received about medication prescribed for bipolar disorder: Implications for informed choice. Journal of Affective Disorders, 100(1−3), 253-257. https://doi.org/10.1016/j.jad.2006.10.018

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