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. 2022 Jul;49(7):672-683.
doi: 10.1111/jcpe.13641. Epub 2022 May 13.

Soft tissue phenotype modification predicts gingival margin long-term (10-year) stability: Longitudinal analysis of six randomized clinical trials

Shayan Barootchi  1   2 , Lorenzo Tavelli  1   2   3 , Riccardo Di Gianfilippo  1 , Kerby Shedden  4   5   6 , Tae-Ju Oh  1 , Giulio Rasperini  1   7 , Rodrigo Neiva  8 , William V Giannobile  3 , Hom-Lay Wang  1
Affiliations

Soft tissue phenotype modification predicts gingival margin long-term (10-year) stability: Longitudinal analysis of six randomized clinical trials

Shayan Barootchi et al. J Clin Periodontol. 2022 Jul.

Abstract

Aim: To assess the prognostic value of soft tissue phenotype modification following root coverage procedures for predicting the long-term (10-year) behaviour of the gingival margin.

Materials and methods: Participants from six randomized clinical trials on root coverage procedures at the University of Michigan were re-invited for a longitudinal evaluation. Clinical measurements were obtained by two calibrated examiners. A data-driven approach to model selection with Akaike information criterion (AIC) was carried out via multilevel regression analyses and partial regression plotting for changes in the level of the gingival margin over time and interactions with the early (6-month) results of soft tissue phenotypic modification.

Results: One-hundred and fifty-seven treated sites in 83 patients were re-assessed at the long-term recall. AIC-driven model selection and regression analyses demonstrated that 6-month keratinized tissue width (KTW) and gingival thickness (GT) influenced the trajectory of the gingival margin similarly in a concave manner; however, GT was the driving determinant that predicted significantly less relapse in the treatments, with stability of the treated gingival margin obtained beyond values of 1.46 mm.

Conclusions: Among a compliant patient cohort, irrespective of the rendered therapy, the presence of at least 1.5 mm KTW and 1.46 mm GT was correlated with the long-term stability of the gingival margin.

Keywords: evidence-based dentistry; gingival recession; periodontitis; root coverage; soft tissue augmentation.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flow chart of this study. ADM, acellular dermal matrix; CAF, coronally advanced flap; CTG, connective tissue graft; EMD, enamel matrix derivative; GTR, guided tissue regeneration; PRP, platelet‐rich plasma; TUN, tunnel technique
FIGURE 2
FIGURE 2
Estimated relationship between 10‐year change in the level of the gingival margin (recession, Rec), and gingival thickness (GT) at 6 months based on the model
See this image and copyright information in PMC

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References

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