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Comment
. 2022 Sep;77(3):874-876.
doi: 10.1016/j.jhep.2022.04.037. Epub 2022 May 11.

Impaired mitochondrial complex IV respiration in peripheral blood mononuclear cells discriminates acute-on-chronic liver failure from acute decompensation

Mona-May Langer  1 , Chantal Eickelmann  2 , Petra Kleinbongard  2 , Christian M Lange  3
Affiliations
Comment

Impaired mitochondrial complex IV respiration in peripheral blood mononuclear cells discriminates acute-on-chronic liver failure from acute decompensation

Mona-May Langer et al. J Hepatol. 2022 Sep.
No abstract available

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Conflict of interest statement

Conflicts of interest The authors have no conflicts of interest to disclose. Please refer to the accompanying ICMJE disclosure forms for further details.

Comment on

  • Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF.
    Moreau R, Clària J, Aguilar F, Fenaille F, Lozano JJ, Junot C, Colsch B, Caraceni P, Trebicka J, Pavesi M, Alessandria C, Nevens F, Saliba F, Welzel TM, Albillos A, Gustot T, Fernández J, Moreno C, Baldassarre M, Zaccherini G, Piano S, Montagnese S, Vargas V, Genescà J, Solà E, Bernal W, Butin N, Hautbergue T, Cholet S, Castelli F, Jansen C, Steib C, Campion D, Mookerjee R, Rodríguez-Gandía M, Soriano G, Durand F, Benten D, Bañares R, Stauber RE, Gronbaek H, Coenraad MJ, Ginès P, Gerbes A, Jalan R, Bernardi M, Arroyo V, Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif). Moreau R, et al. J Hepatol. 2020 Apr;72(4):688-701. doi: 10.1016/j.jhep.2019.11.009. Epub 2019 Nov 25. J Hepatol. 2020. PMID: 31778751
  • Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure.
    Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J. Zhang IW, et al. J Hepatol. 2022 Jan;76(1):93-106. doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25. J Hepatol. 2022. PMID: 34450236

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