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. 2022 May 13;13(1):2678.
doi: 10.1038/s41467-022-30133-w.

Malaria in 2022: Increasing challenges, cautious optimism

Affiliations

Malaria in 2022: Increasing challenges, cautious optimism

Prasanna Jagannathan et al. Nat Commun. .

Abstract

Malaria cases and deaths remain unacceptably high and are resurgent in several settings, though recent developments inspire optimism. This includes the approval of the world’s first malaria vaccine and results from novel vaccine candidates and trials testing innovative combinatorial interventions.

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Conflict of interest statement

The authors declare no competing interests.

References

    1. WHO. World Malaria Report, 2021. (World Health Organization, 2021).
    1. Bhatt S, et al. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015;526:207–211. doi: 10.1038/nature15535. - DOI - PMC - PubMed
    1. Ashley EA, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N. Engl. J. Med. 2014;371:411–423. doi: 10.1056/NEJMoa1314981. - DOI - PMC - PubMed
    1. Phyo AP, et al. Declining efficacy of artemisinin combination therapy Against P. Falciparum malaria on the Thai-Myanmar Border (2003–2013): the role of parasite genetic factors. Clin. Infect. Dis. 2016;63:784–791. doi: 10.1093/cid/ciw388. - DOI - PMC - PubMed
    1. Uwimana A, et al. Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda. Nat. Med. 2020;26:1602–1608. doi: 10.1038/s41591-020-1005-2. - DOI - PMC - PubMed