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Review
. 2022 Apr 26;23(9):4760.
doi: 10.3390/ijms23094760.

Insight into the Role of Psychological Factors in Oral Mucosa Diseases

Yuexin Guo  1 , Boya Wang  2 , Han Gao  3 , Chengwei He  3 , Rongxuan Hua  4 , Lei Gao  5 , Yixuan Du  1 , Jingdong Xu  3
Affiliations
Review

Insight into the Role of Psychological Factors in Oral Mucosa Diseases

Yuexin Guo et al. Int J Mol Sci. .

Abstract

With the development of psychology and medicine, more and more diseases have found their psychological origins and associations, especially ulceration and other mucosal injuries, within the digestive system. However, the association of psychological factors with lesions of the oral mucosa, including oral squamous cell carcinoma (OSCC), burning mouth syndrome (BMS), and recurrent aphthous stomatitis (RAS), have not been fully characterized. In this review, after introducing the association between psychological and nervous factors and diseases, we provide detailed descriptions of the psychology and nerve fibers involved in the pathology of OSCC, BMS, and RAS, pointing out the underlying mechanisms and suggesting the clinical indications.

Keywords: disease; interactions; oral mucosa; pathology; psychology.

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Conflict of interest statement

The authors declare no conflict of interest.

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Supplementary concepts