Motor abnormalities in weaver mutant mice
- PMID: 3556474
- DOI: 10.1007/BF00236322
Motor abnormalities in weaver mutant mice
Abstract
Weaver mutant mice lose mainly cerebellar granule cells. Motor abnormalities included less activity in a hole-board test and a loss of balance in two equilibrium tests. It was noted that the weaver mutants also displayed paw clasping responses when held by the tail of a sort never seen in normal mice. The role of the cerebellum in these abnormalities is discussed.