Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Apr 20;14(9):1712.
doi: 10.3390/nu14091712.

Clinical Evidence of the Benefits of Phytonutrients in Human Healthcare

Affiliations
Review

Clinical Evidence of the Benefits of Phytonutrients in Human Healthcare

Nicolas Monjotin et al. Nutrients. .

Abstract

Phytonutrients comprise many different chemicals, including carotenoids, indoles, glucosinolates, organosulfur compounds, phytosterols, polyphenols, and saponins. This review focuses on the human healthcare benefits of seven phytochemical families and highlights the significant potential contribution of phytonutrients in the prevention and management of pathologies and symptoms in the field of family health. The structure and function of these phytochemical families and their dietary sources are presented, along with an overview of their potential activities across different health and therapeutic targets. This evaluation has enabled complementary effects of the different families of phytonutrients in the same area of health to be recognized.

Keywords: anthocyanins; caffeine; carotenoids; flavonoids; healthcare; organosulfur compounds; phenolic acids; phytonutrients; tannins.

PubMed Disclaimer

Conflict of interest statement

M.J. Amiot, J. Fleurentin and J.M. Morel have acted as consultants for, and as expert witnesses on behalf of, Pierre Fabre Laboratories, France. N. Monjotin and S. Raynal are employees of Pierre Fabre Laboratories, France.

Figures

Figure 1
Figure 1
Literature search methodology.
Figure 2
Figure 2
Classification of the main phytonutrient families (modified from [6]). Dark grey: Phytonutrients Families. Light grey: Phytonutrients examples.
Figure 3
Figure 3
Main phytonutrient family chemical structures.

Similar articles

Cited by

References

    1. Zaynab M., Fatima M., Abbas S., Sharif Y., Umair M., Zafar M.H., Bahadar K. Role of secondary metabolites in plant defense against pathogens. Microb. Pathog. 2018;124:198–202. doi: 10.1016/j.micpath.2018.08.034. - DOI - PubMed
    1. Slavin J.L., Lloyd B. Health benefits of fruits and vegetables. Adv. Nutr. 2012;3:506–516. doi: 10.3945/an.112.002154. - DOI - PMC - PubMed
    1. Maggini S., Pierre A., Calder P.C. Immune function and micronutrient requirements change over the life course. Nutrients. 2018;10:1531. doi: 10.3390/nu10101531. - DOI - PMC - PubMed
    1. Poiroux-Gonord F., Bidel L.P., Fanciullino A.L., Gautier H., Lauri-Lopez F., Urban L. Health benefits of vitamins and secondary metabolites of fruits and vegetables and prospects to increase their concentrations by agronomic approaches. J. Agric. Food Chem. 2010;58:12065–12082. doi: 10.1021/jf1037745. - DOI - PubMed
    1. Aune D. Plant foods, antioxidant biomarkers, and the risk of cardiovascular disease, cancer, and mortality: A review of the evidence. Adv. Nutr. 2019;10((Suppl. 4)):S404–S421. doi: 10.1093/advances/nmz042. - DOI - PMC - PubMed

LinkOut - more resources