Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 May 6;11(9):2589.
doi: 10.3390/jcm11092589.

Negative-Pressure Ventilation in Neuromuscular Diseases in the Acute Setting

Anna Annunziata  1 , Cecilia Calabrese  2 , Francesca Simioli  1 , Antonietta Coppola  1 , Martina Flora  1 , Antonella Marotta  1 , Valentina Di Spirito  1 , Francesco Didonna  1 , Marcellino Cicalese  3 , Giuseppe Fiorentino  1
Affiliations
Review

Negative-Pressure Ventilation in Neuromuscular Diseases in the Acute Setting

Anna Annunziata et al. J Clin Med. .

Abstract

Mechanical ventilation started with negative-pressure ventilation (NPV) during the 1950s to assist patients with respiratory failure, secondary to poliomyelitis. Over the years, technological evolution has allowed for the development of more comfortable devices, leading to an increased interest in NPV. The patients affected by neuromuscular diseases (NMD) with chronic and acute respiratory failure (ARF) may benefit from NPV. The knowledge of the available respiratory-support techniques, indications, contraindications, and adverse effects is necessary to offer the patient a personalized treatment that considers the pathology's complexity.

Keywords: cuirass; iron lung; negative-pressure ventilation; neuromuscular diseases; poncho.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
A patient with ALS during NPV.
See this image and copyright information in PMC

References

    1. Drinker P.A., McKhann C.F. The Iron Lung: First practical means of respiratory support. JAMA. 1986;255:1476–1480. doi: 10.1001/jama.1986.03370110098030. - DOI - PubMed
    1. Emerson J.H. The Evolution of Iron Lungs. JH Emerson Co.; Cambridge, MA, USA: 1978.
    1. Kinnear W., Petch M., Taylor G., Shneerson J. Assisted ventilation using cuirass respirators. Eur. Respir. J. 1988;1:198–203. - PubMed
    1. Corrado A., Gorini M., Villella G., De Paola E. Negative pressure ventilation in the treatment of acute respiratory failure: An old noninvasive technique reconsidered. Eur. Respir. J. 1996;9:1531–1544. doi: 10.1183/09031936.96.09071531. - DOI - PubMed
    1. Kinnear W., Hockley S., Harvey J., Shneerson J. The effects of one year of nocturnal cuirass-assisted ventilation in chest wall disease. Eur. Respir. J. 1988;1:204–208. - PubMed

LinkOut - more resources