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Review
. 2022 May 5;11(9):1244.
doi: 10.3390/plants11091244.

Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review

Cristina Burlou-Nagy  1   2 , Florin Bănică  2 , Tünde Jurca  2 , Laura Grațiela Vicaș  2 , Eleonora Marian  2 , Mariana Eugenia Muresan  3 , Ildikó Bácskay  4 , Rita Kiss  5 , Pálma Fehér  4 , Annamaria Pallag  2
Affiliations
Review

Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review

Cristina Burlou-Nagy et al. Plants (Basel). .

Abstract

Echinacea purpurea (L.) Moench (EP)is a perennial herbaceous flowering plant, commonly known as purple coneflower and it belongs to the Asteraceae family. The Echinacea genus is originally from North America, in the United States, and its species are widely distributed throughout. There are nine different species of Echinacea, but only three of them are used as medicinal plants with wide therapeutic uses: Echinacea purpurea (L.) Moench, Echinacea pallida (Nutt.) Nutt. and Echinacea angustifolia DC. Several significant groups of bioactive compounds with pharmacological activities have been isolated from Echinacea species. Numerous beneficial effects have been demonstrated about these compounds. The immunomodulatory effect was initially demonstrated, but over time other effects have also been highlighted. The present review gives a comprehensive summary of the chemical constituents, bioactive compounds, biological effects and therapeutical uses of purple coneflower. Research shows that such a well-known and recognized species needs to be further studied to obtain efficient products with a guarantee of the safety.

Keywords: Echinacea purpurea (L.) Moench; anti-inflammatory; antimicrobial; antioxidant effect; antiviral; bioactive compounds; cannabinomimetic; immunomodulatory.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Evolution of the number of articles and reviews about Echinacea sp. and Echinacea purpurea (L.) Moench [9,10].
Figure 2
Figure 2
Publications by scientific categories indexed in Scopus [9].
Figure 3
Figure 3
Prisma flow diagram for a description of the selection process of the bibliographic sources.
Figure 4
Figure 4
Structure of major compounds.
Figure 5
Figure 5
Properties of Echinacea purpurea (L.) Moench.
See this image and copyright information in PMC

References

    1. Salmeron-Manzano E., Garrido-Cardenas J.A., Manzano-Agugliaro F. Worldwide Research Trends on Medicinal Plants. Int. J. Environ. Res. Public Health. 2020;17:3376. doi: 10.3390/ijerph17103376. - DOI - PMC - PubMed
    1. Pazyar N., Yaghoobi R., Rafiee E., Mehrabian A., Feily A. Skin Wound Healing and Phytomedicine: A Review. Ski. Pharmacol. Physiol. 2014;27:303–310. doi: 10.1159/000357477. - DOI - PubMed
    1. Hegedűs C., Muresan M., Badale A., Bombicz M., Varga B., Szilágyi A., Sinka D., Bácskay I., Popoviciu M., Magyar I., et al. SIRT1 Activation by Equisetum arvense L. (Horsetail) Modulates Insulin Sensitivity in Streptozotocin Induced Diabetic Rats. Molecules. 2020;25:2541. doi: 10.3390/molecules25112541. - DOI - PMC - PubMed
    1. Stanisavljević I., Stojičević S., Veličković D., Veljković V., Lazic M. Antioxidant and Antimicrobial Activities of Echinacea (Echinacea purpurea L.) Extracts Obtained by Classical and Ultrasound Extraction. Chin. J. Chem. Eng. 2009;17:478–483. doi: 10.1016/S1004-9541(08)60234-7. - DOI
    1. Kaya M., Merdivan M., Tashakkori P., Erdem P., Anderson J.L. Analysis of Echinacea flower volatile constituents by HS-SPME-GC/MS using laboratory-prepared and commercial SPME fibers. J. Essent. Oil Res. 2018;31:91–98. doi: 10.1080/10412905.2018.1545707. - DOI

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