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Review
. 2022 May 5;11(9):1249.
doi: 10.3390/plants11091249.

Cyano-Phycocyanin: Mechanisms of Action on Human Skin and Future Perspectives in Medicine

Daiva Dranseikienė  1 , Gabrielė Balčiūnaitė-Murzienė  2 , Jūratė Karosienė  3 , Dmitrij Morudov  3 , Nomeda Juodžiukynienė  4 , Nataliia Hudz  5   6 , Rima Jūratė Gerbutavičienė  7 , Nijolė Savickienė  1
Affiliations
Review

Cyano-Phycocyanin: Mechanisms of Action on Human Skin and Future Perspectives in Medicine

Daiva Dranseikienė et al. Plants (Basel). .

Abstract

Cyano-phycocyanin is one of the active pigments of the blue-green algae and is usually isolated from the filamentous cyanobacteria Arthrospira platensis Gomont (Spirulina). Due to its multiple physiological functions and non-toxicity, cyano-phycocyanin may be a potential substance for the topical treatment of various skin diseases. Considering that the conventional medicine faces drug resistance, insufficient efficacy and side effects, the plant origin compounds can act as an alternative option. Thus, the aim of this paper was to review the wound healing, antimicrobial, antioxidative, anti-inflammatory, antimelanogenic and anticancer properties and mechanisms of cyano-phycocyanin topical activities on human skin. Moreover, possible applications and biotechnological requirements for pharmaceutical forms of cyano-phycocyanin for the treatment of various skin diseases are discussed in this review.

Keywords: anti-inflammatory effect; anticancer effect; antimelanogenic effect; antimicrobial effect; antioxidative activity; cyano-phycocyanin; cyanobacteria; skin diseases; wound healing.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of the present article.

Figures

Figure 1
Figure 1
Physiological properties of C-PC for the topical application.
See this image and copyright information in PMC

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