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Comment
. 2022 Aug;92(2):340-341.
doi: 10.1002/ana.26408. Epub 2022 May 30.

Continued False-Positive Detection of SARS-CoV-2 by Electron Microscopy

Carsten Dittmayer  1 , Michael Laue  2
Affiliations
Comment

Continued False-Positive Detection of SARS-CoV-2 by Electron Microscopy

Carsten Dittmayer et al. Ann Neurol. 2022 Aug.
No abstract available

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Conflict of interest statement

Nothing to report.

Figures

FIGURE 1
FIGURE 1
Ultrastructure of coronavirus particles in autopsy lung. Well‐preserved coronavirus (CV) particles are highlighted by black arrowheads. The most characteristic feature of CV particles in thin section electron microscopy is the electron dense appearance and granular substructure due to presence of ribonucleoprotein (black arrows), whereas “spikes” reveal a faint contrast with a prominent globular head (white arrowheads). Intracellular CV particles are enclosed in membrane‐bound compartments (white arrows) that may be ruptured, like in image (A), due to, for example, autolysis, thus also limiting cell type assessment. See Krasemann et al. for detailed recommendations of CV particle identification and information on the sample. Digitized thin sections and regions of autopsy lung are available online for open access pan‐and‐zoom analysis (www.nanotomy.org).
See this image and copyright information in PMC

Comment on

References

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