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. 2022:1365:1-6.
doi: 10.1007/978-981-16-8387-9_1.

Overview: Themes in Innate Lymphoid Cell Biology

Marco Colonna  1
Affiliations

Overview: Themes in Innate Lymphoid Cell Biology

Marco Colonna. Adv Exp Med Biol. 2022.

Abstract

Since their initial identification more than 10 years ago, innate lymphoid cells (ILCs) have emerged as denizens of an immune realm parallel to that of T cells. Here I highlight basic similarities shared by all and underscore features related to development, tissue residency and regulation that distinguish ILCs from T cells. I further discuss the potential of ILCs as promising targets for therapeutic intervention in human diseases.

Keywords: Cytokines; Human; Innate lymphoid cells; Regulation; Therapy.

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