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. 2022 Apr;52(2):214-227.
doi: 10.4040/jkan.21188.

[Incidence and Risk Factors of Dyslipidemia after Menopause]

[Article in Korean]
Ihn Sook Jeong  1 , Hae Sun Yun  2 , Myo Sung Kim  3 , Youn Sun Hwang  4
Affiliations

[Incidence and Risk Factors of Dyslipidemia after Menopause]

[Article in Korean]
Ihn Sook Jeong et al. J Korean Acad Nurs. 2022 Apr.

Abstract

Purpose: This study was aimed at investigating the incidence and risk factors of dyslipidemia in menopausal women using a Korean community-based longitudinal study.

Methods: The subjects were 245 postmenopausal women without dyslipidemia who had participated in the Ansan-Ansung cohort study from 2001~2002 (baseline) to 2015~2016 (seventh follow-up visit). The dyslipidemia incidence was measured as incidence proportion (%) and incidence rate per 100 person-years. The predictors of developing dyslipidemia were analyzed with Cox's proportional hazard model.

Results: The incidence of new dyslipidemia during the follow-up period was 78.4% (192 patients), and 11.9 per 100 person-years. Mean duration from menopause to developing dyslipidemia was 5.3 years in new dyslipidemia cases. The triglyceride/high density lipoprotein (TG/HDL-C) ratio at baseline (hazard ratio = 2.20; 95% confidence interval = 1.39~3.48) was independently associated with developing dyslipidemia.

Conclusion: Dyslipidemia occurs frequently in postmenopausal women, principally within five years after menopause. Therefore, steps must be taken to prevent dyslipidemia immediately after menopause, particularly in women with a high TG/HDL-C ratio at the start of menopause.

Keywords: Dyslipidemias; Incidence; Menopause; Risk Factors.

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Conflict of interest statement

The authors declared no conflict of interest.

References

    1. Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk. European Heart Journal 2020;41(1):111–188. - PubMed
    1. Statistics Korea. 2019 causes of death statistics [Internet]. Daejeon: Statistics Korea; c2020 [cited 2021 Jul 28]. Available from: http://kostat.go.kr/portal/korea/kor_nw/1/6/2/index.board?bmode=read&amp...
    1. Lu Y, Wang P, Zhou T, Lu J, Spatz ES, Nasir K, et al. Comparison of prevalence, awareness, treatment, and control of cardiovascular risk factors in China and the United States. Journal of the American Heart Association 2018;7(3):e007462. - PMC - PubMed
    1. Halcox JP, Banegas JR, Roy C, Dallongeville J, De Backer G, Guallar E, et al. Prevalence and treatment of atherogenic dyslipidemia in the primary prevention of cardiovascular disease in Europe: EURIKA, a cross-sectional observational study. BMC Cardiovascular Disorders 2017;17(1):160. - PMC - PubMed
    1. Xing L, Jing L, Tian Y, Yan H, Zhang B, Sun Q, et al. Epidemiology of dyslipidemia and associated cardiovascular risk factors in northeast China: A cross-sectional study. Nutrition Metabolism and Cardiovascular Diseases 2020;30(12):2262–2270.

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