Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022:1377:163-170.
doi: 10.1007/978-981-19-1592-5_13.

HDL and Kidney Diseases

Huanhuan Cao  1 , Xia Meng  2
Affiliations

HDL and Kidney Diseases

Huanhuan Cao et al. Adv Exp Med Biol. 2022.

Abstract

Serum lipid profiles, as well as HDL can be altered in patients with kidney diseases. There are various types of kidney diseases, including nephrotic syndrome and chronic kidney disease. In patients with nephrotic syndrome, plasma levels of HDL cholesterol and ApoA-I were within or below the normal limits. The HDL cholesterol: total cholesterol ratio decreased compared to healthy individuals. In patients with chronic kidney disease (CKD), reverse cholesterol transport function of HDL is impaired, and CKD also affects the composition and function of HDL. Cardiovascular disease (CVD) is the severe complication of CKD. Furthermore, HDL might also be a potential target for the prevention of cardiovascular complications associated with CKD.

Keywords: Chronic kidney disease; HDL; Nephrotic syndrome.

PubMed Disclaimer

References

    1. Keane WF, Lyle PA (2005) Kidney disease and cardiovascular disease: implications of dyslipidemia. Cardiol Clin 23(3):363–372 - PubMed - DOI
    1. Banh TH et al (2016) Ethnic differences in incidence and outcomes of childhood nephrotic syndrome. Clin J Am Soc Nephrol 11(10):1760–1768 - PubMed - PMC - DOI
    1. Sethna CB, Merchant K, Reyes A (2018) Cardiovascular disease risk in children with kidney disease. Semin Nephrol 38(3):298–313 - PubMed - DOI
    1. Liebeskind DS (2014) Nephrotic syndrome. Handb Clin Neurol 119:405–415 - PubMed - DOI
    1. van den Berg JG, Weening JJ (2004) Role of the immune system in the pathogenesis of idiopathic nephrotic syndrome. Clin Sci (Lond) 107(2):125–136 - DOI

Substances

LinkOut - more resources