Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Dec;29(12):653-654.
doi: 10.1038/s41434-022-00340-7. Epub 2022 May 17.

Optimized expression of alternative oxidase

Jiri Neuzil  1   2
Affiliations
Comment

Optimized expression of alternative oxidase

Jiri Neuzil. Gene Ther. 2022 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declares no competing interests.

Comment on

Similar articles

See all similar articles

References

    1. Giordano L, Aneja MK, Sommer N, Alebrahimdehkordi N, Seraji A, Weissmann N, et al. Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active. Gene Ther. 2021. 10.1038/s41434-021-00235-z. - PMC - PubMed
    1. Dassa EP, Dufour E, Goncalves S, Paupe V, Hakkaart GAJ, Jacobs HT, et al. Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells. EMBO Mol Med. 2009;1:30–36. doi: 10.1002/emmm.200900001. - DOI - PMC - PubMed
    1. Fernandez-Ayala DJM, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, et al. Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab. 2009;9:449–60. doi: 10.1016/j.cmet.2009.03.004. - DOI - PubMed
    1. Hakkaart GA, Dassa EP, Jacobs HT, Rustin P. Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration. EMBO Rep. 2006;7:341–5. doi: 10.1038/sj.embor.7400601. - DOI - PMC - PubMed
    1. Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, et al. Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med. 2019;11:e9456. doi: 10.15252/emmm.201809456. - DOI - PMC - PubMed