Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser
- PMID: 35580249
- DOI: 10.1097/DSS.0000000000003491
Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser
Abstract
Background: Infantile hemangioma (IH) often causes cosmetic disfigurement. Early intervention with propranolol for large, high-risk lesions is recommended in the American Academy of Pediatrics' Clinical Practice Guideline. Conversely, strategies for the management of small, low-risk lesions have not been established; however, pulsed dye laser (PDL) is often used to treat these lesions.
Objective: To investigate clinical outcomes of PDL in small IH lesions.
Patients and methods: Fifty-three cases with 58 small IHs which did not meet the criteria for high-risk lesions in the guideline and were treated only with PDL were retrospectively reviewed. The characteristics of IHs and residual skin changes after treatment were evaluated.
Results: Forty-seven lesions (81.0%) were superficial hemangiomas, whereas 11 (19.0%) were combined-type. The median maximum diameter was 10.0 mm. Forty-five lesions (77.6%) exhibited various residual skin changes after PDL treatment, including anetoderma (53.5%), telangiectasia and erythema (43.1%), hyperpigmentation (34.5%), redundant skin (3.4%), and fibrofatty tissue (3.4%). Of these, the incidence of anetoderma and fibrofatty tissue were significantly higher in the combined group than in the superficial group ( p = .036 and .033, respectively).
Conclusion: Even small lesions, especially combined-type, often result in cosmetic problems after PDL treatment.
Copyright © 2022 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Comment on
-
Clinical Practice Guideline for the Management of Infantile Hemangiomas.Pediatrics. 2019 Jan;143(1):e20183475. doi: 10.1542/peds.2018-3475. Pediatrics. 2019. PMID: 30584062 Review.
References
-
- Krowchuk DP, Frieden IJ, Mancini AJ, Darrow DH, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics 2019;143:e20183475.
-
- Chang SJ, Qiao C, Chang L, Gao W, et al. A 7-year follow-up study on untreated deep or mixed facial infantile hemangioma in East-Asian patients: when propranolol was not yet an option. J Dermatol 2019;46:962–6.
-
- Baselga E, Roe E, Coulie J, Munoz FZ, et al. Risk factors for degree and type of sequelae after involution of untreated hemangiomas of infancy. JAMA Dermatol 2016;152:1239–43.
-
- Wang C, Li Y, Xiang B, Xiong F, et al. Quality of life in children with infantile hemangioma: a case control study. Health Qual Life Outcomes 2017;15:221.
-
- Drolet BA, Boakye-Agyeman F, Harper B, Holland K, et al. Systemic timolol exposure following topical application to infantile hemangiomas. J Am Acad Dermatol 2020;82:733–6.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
