Symptomatic Care in Multiple System Atrophy: State of the Art
- PMID: 35581488
- PMCID: PMC10125958
- DOI: 10.1007/s12311-022-01411-6
Symptomatic Care in Multiple System Atrophy: State of the Art
Abstract
Without any disease-modifying treatment strategy for multiple system atrophy (MSA), the therapeutic management of MSA patients focuses on a multidisciplinary strategy of symptom control. In the present review, we will focus on state of the art treatment in MSA and additionally give a short overview about ongoing randomized controlled trials in this field.
Keywords: Autonomic dysfunction; Motor and non-motor symptoms; Multiple system atrophy; Symptomatic treatment.
© 2022. The Author(s).
Conflict of interest statement
KS reports personal fees from Teva, UCB, Lundbeck, AOP Orphan Pharmaceuticals AG, Roche, Gruenenthal, Stada, Lucher Pharma, Biogen, BIAL, and AbbVie, and honoraria from the International Parkinson and Movement Disorders Society. All other authors declare no competing interests.
Similar articles
-
Progression and prognosis in multiple system atrophy: an analysis of 230 Japanese patients.Brain. 2002 May;125(Pt 5):1070-83. doi: 10.1093/brain/awf117. Brain. 2002. PMID: 11960896 Review.
-
[Expanding concept of clinical conditions and symptoms in multiple system atrophy].Rinsho Shinkeigaku. 2016 Jul 28;56(7):457-64. doi: 10.5692/clinicalneurol.cn-000903. Epub 2016 Jun 30. Rinsho Shinkeigaku. 2016. PMID: 27356737 Review. Japanese.
-
Natural history of multiple system atrophy in the USA: a prospective cohort study.Lancet Neurol. 2015 Jul;14(7):710-9. doi: 10.1016/S1474-4422(15)00058-7. Epub 2015 May 27. Lancet Neurol. 2015. PMID: 26025783 Free PMC article.
-
Multiple System Atrophy - State of the Art.Curr Neurol Neurosci Rep. 2017 May;17(5):41. doi: 10.1007/s11910-017-0751-0. Curr Neurol Neurosci Rep. 2017. PMID: 28378233 Review.
-
Various Motor and Non-Motor Symptoms in Early Multiple System Atrophy.Neurodegener Dis. 2019;19(5-6):238-243. doi: 10.1159/000507292. Epub 2020 Apr 29. Neurodegener Dis. 2019. PMID: 32348986
Cited by
-
Pain in Multiple System Atrophy a Systematic Review and Meta-Analysis.Mov Disord Clin Pract. 2023 Oct 18;10(12):1738-1749. doi: 10.1002/mdc3.13897. eCollection 2023 Dec. Mov Disord Clin Pract. 2023. PMID: 38094640 Free PMC article. Review.
-
Multiple system atrophy: an update and emerging directions of biomarkers and clinical trials.J Neurol. 2024 May;271(5):2324-2344. doi: 10.1007/s00415-024-12269-5. Epub 2024 Mar 14. J Neurol. 2024. PMID: 38483626 Free PMC article. Review.
-
Inflammation in multiple system atrophy.Front Immunol. 2023 Jun 22;14:1214677. doi: 10.3389/fimmu.2023.1214677. eCollection 2023. Front Immunol. 2023. PMID: 37426656 Free PMC article. Review.
-
Glutathione Depletion and MicroRNA Dysregulation in Multiple System Atrophy: A Review.Int J Mol Sci. 2022 Dec 1;23(23):15076. doi: 10.3390/ijms232315076. Int J Mol Sci. 2022. PMID: 36499400 Free PMC article. Review.
-
Multiple system atrophy.Nat Rev Dis Primers. 2022 Aug 25;8(1):56. doi: 10.1038/s41572-022-00382-6. Nat Rev Dis Primers. 2022. PMID: 36008429 Review.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources