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. 2023 Dec:64 Suppl 4:S4-S11.
doi: 10.1111/epi.17307. Epub 2022 Jun 6.

Diagnostic yield and limitations of in-hospital documentation in patients with epilepsy

Andreas Schulze-Bonhage  1   2 , Elisa Bruno  3 , Armin Brandt  1 , Anthony Shek  3 , Pedro Viana  3 , Marcel Heers  1   2 , Eva Martinez-Lizana  1   2 , Dirk-Matthias Altenmüller  1 , Mark Philip Richardson  3 , Victoria San Antonio-Arce  1   2
Affiliations

Diagnostic yield and limitations of in-hospital documentation in patients with epilepsy

Andreas Schulze-Bonhage et al. Epilepsia. 2023 Dec.

Abstract

Objective: To determine the diagnostic yield of in-hospital video-electroencephalography (EEG) monitoring to document seizures in patients with epilepsy.

Methods: Retrospective analysis of electronic seizure documentation at the University Hospital Freiburg (UKF) and at King's College London (KCL). Statistical assessment of the role of the duration of monitoring, and subanalyses on presurgical patient groups and patients undergoing reduction of antiseizure medication.

Results: Of more than 4800 patients with epilepsy undergoing in-hospital recordings at the two institutions since 2005, seizures with documented for 43% (KCL) and 73% (UKF).. Duration of monitoring was highly significantly associated with seizure recordings (p < .0001), and presurgical patients as well as patients with drug reduction had a significantly higher diagnostic yield (p < .0001). Recordings with a duration of >5 days lead to additional new seizure documentation in only less than 10% of patients.

Significance: There is a need for the development of new ambulatory monitoring strategies to document seizures for diagnostic and monitoring purposes for a relevant subgroup of patients with epilepsy in whom in-hospital monitoring fails to document seizures.

Keywords: epilepsy; ictal event; in-hospital monitoring; mobile devices; seizure; video-EEG.

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Conflict of interest statement

Andreas Schulze-Bonhage has received research support from the company UNEEG as part of a multicenter ongoing study. None of the other authors has any conflict of interest to disclose. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.

References

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