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. 2022 Jun 1;20(21):4314-4319.
doi: 10.1039/d2ob00439a.

Chirality-driven self-assembly: application toward renewable/exchangeable resin-immobilized catalysts

Elizabeth M Menuey  1 , John Zhou  1 , Shuyuan Tian  1 , Reid E Brenner  1 , Zhaoyang Ren  2 , Duy H Hua  2 , Kathleen V Kilway  1 , Shin A Moteki  1
Affiliations

Chirality-driven self-assembly: application toward renewable/exchangeable resin-immobilized catalysts

Elizabeth M Menuey et al. Org Biomol Chem. .

Abstract

Resin-immobilized catalysts were prepared through chirality-driven self-assembly. The method allows the resin-immobilized catalyst to be regenerated under mild conditions and in situ catalyst exchange to be carried out quantitatively. The uniqueness of the methodology was demonstrated by the preparation of a catalyst for TEMPO oxidation as well as a two-step sequential TEMPO oxidation/aldol condensation sequence enabled by facile catalyst exchange.

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Conflict of interest statement

Conflicts of interest

There are no conflicts to declare.

Figures

Scheme 1
Scheme 1
Non-selective (A and B) versus selective self-assembly (C and D).
Scheme 2
Scheme 2
Renewability and exchangeability of the self-assembly based resin immobilized catalysts.
Scheme 3
Scheme 3
One-pot preparation of fmoc-derived resin used for quantifying the functional capacity.
Scheme 4
Scheme 4
Renewability and exchangeability of the self-assembly based resin immobilized catalysts.
Scheme 5
Scheme 5
A one-pot preparation of resin immobilized TEMPO catalyst (RR,RR)-11.
Scheme 6
Scheme 6
Sequential oxidation/aldol reaction using catalyst exchangeable resin.
See this image and copyright information in PMC

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