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Comment
. 2022 May 13;3(5):273-275.
doi: 10.1016/j.medj.2022.04.008. Epub 2022 May 13.

Restoring type VII collagen in skin

Su M Lwin  1 , John A McGrath  2
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Restoring type VII collagen in skin

Su M Lwin et al. Med. .
Free article

Abstract

New therapeutic hope is emerging for people with the rare inherited blistering skin disease recessive dystrophic epidermolysis bullosa (RDEB). Gurevich et al.1 have reported early-phase clinical trial data evaluating a topical herpes simplex virus 1 vector to restore missing type VII collagen in RDEB skin and heal wounds.

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Conflict of interest statement

Declaration of interests The authors have received educational grants from Amryt Pharma (J.A.M.) and Janssen (S.M.L.) and have undertaken paid consulting work for Replay (J.A.M.), Almirall (J.A.M.), La Roche Posay (J.A.M.), and Pierre Fabre (J.A.M.).

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