Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jun 16;4(2):79-81.
doi: 10.1007/BF00775964.

Dissociability of free and peptidyl-tRNA bound ribosomes

A P Surguchov, E S Fominykch, L V Lyzlova

Dissociability of free and peptidyl-tRNA bound ribosomes

A P Surguchov et al. Mol Biol Rep. .

Abstract

The influence of peptidyl-tRNA on the dissociation of yeast 80 S ribosomes into subunits was studied. For this purpose temperature-sensitive (ts) suppressor strain of yeast Saccharomyces cervisiae carrying a defect in peptide chain termination was used. It was found that peptidyl-tRNA did not influence the dissociation of ribosomes either at high salt concentration or in the presence of dissociation factor (DF) from yeast. After dissociation of yeast ribosomes in 0.5 M KCl, peptidyl-tRNA remains bound to the 60 S subunit. Some characteristics of the termination process and release of nascent polypeptides from yeast ribosomes are discussed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Eur J Biochem. 1976 Feb 2;62(1):193-7 - PubMed
    1. J Bacteriol. 1976 Mar;125(3):1074-9 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1969;34:223-30 - PubMed
    1. Eur J Biochem. 1972 Oct 17;30(1):15-25 - PubMed
    1. FEBS Lett. 1976 Jul 1;66(1):12-5 - PubMed

MeSH terms

LinkOut - more resources