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. 2022 May 16;8(2):00609-2021.
doi: 10.1183/23120541.00609-2021. eCollection 2022 Apr.

Vitamin D replacement in children with acute wheeze: a dose-escalation study

Christos Stefanidis  1 , Andrew Bush  2 , Christopher Newby  1 , Chinedu Nwokoro  1 , Susan Liebeschuetz  3 , Imogen P Skene  4 , Christopher J Griffiths  1 , Adrian R Martineau  1
Affiliations

Vitamin D replacement in children with acute wheeze: a dose-escalation study

Christos Stefanidis et al. ERJ Open Res. .

Abstract

Vitamin D supplementation at the current UK recommended level (400 IU·day-1) or enhanced supplementation (1000 IU·day-1) failed to achieve adequate levels of vitamin D (>75 nmol·L-1) in vitamin-D-insufficient children with acute wheeze https://bit.ly/3J43Ouo.

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Conflict of interest statement

Conflict of interest: All authors have nothing to disclose.

Figures

FIGURE 1
FIGURE 1
25-hydroxyvitamin D (25(OH)D) concentrations by study time-point in a) all participants (n=31), b) the subset of participants with preschool wheeze (n=15) and c) the subset of participants with school-age asthma (n=16). The dotted line represents the threshold denoting optimal 25(OH)D concentration (>75 nmol·L−1). p-values from paired t-tests.
See this image and copyright information in PMC

References

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