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Comment
. 2022 May;37(5):1121-1122.
doi: 10.1002/mds.29003.

Reply to: "Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood"

Jeannette Hübener-Schmid  1   2 , Kirsten Kuhlbrodt  3 , Julien Peladan  3 ; European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative (ESMI) Study Group; Olaf Rieß  1   2
Affiliations
Comment

Reply to: "Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood"

Jeannette Hübener-Schmid et al. Mov Disord. 2022 May.
No abstract available

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References

    1. Hubener-Schmid J, Kuhlbrodt K, Peladan J, et al. Polyglutamine-expanded Ataxin-3: a target engagement marker for spinocerebellar ataxia type 3 in peripheral blood. Mov Disord 2021;36(11):2675-2681.
    1. Prudencio M, Garcia-Moreno H, Jansen-West KR, et al. Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Sci Transl Med 2020;12(566):eabb7086
    1. Miller J, Arrasate M, Brooks E, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol 2011;7(12):925-934.
    1. Klein FAC, Zeder-Lutz G, Cousido-Siah A, et al. Linear and extended: a common polyglutamine conformation recognized by three antibodies MW1, 1C2 and 3B5H10. Hum Mol Genet 2013;22(20):4215-4223.
    1. Owens EG, New DM, West AP Jr, Bjorkman PJ. Anti-PolyQ antibodies recognize a short polyQ stretch in both normal and mutant huntingtin exon 1. J Mol Biol 2015;427(15):2507-2519.

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