Reply to: "Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood"
- PMID: 35587632
- DOI: 10.1002/mds.29003
Reply to: "Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood"
Comment on
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Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.Mov Disord. 2021 Nov;36(11):2675-2681. doi: 10.1002/mds.28749. Epub 2021 Aug 16. Mov Disord. 2021. PMID: 34397117
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Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.Mov Disord. 2022 May;37(5):1120-1121. doi: 10.1002/mds.29008. Mov Disord. 2022. PMID: 35587620 No abstract available.
References
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- Hubener-Schmid J, Kuhlbrodt K, Peladan J, et al. Polyglutamine-expanded Ataxin-3: a target engagement marker for spinocerebellar ataxia type 3 in peripheral blood. Mov Disord 2021;36(11):2675-2681.
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- Prudencio M, Garcia-Moreno H, Jansen-West KR, et al. Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Sci Transl Med 2020;12(566):eabb7086
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- Miller J, Arrasate M, Brooks E, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol 2011;7(12):925-934.
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- Klein FAC, Zeder-Lutz G, Cousido-Siah A, et al. Linear and extended: a common polyglutamine conformation recognized by three antibodies MW1, 1C2 and 3B5H10. Hum Mol Genet 2013;22(20):4215-4223.
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- Owens EG, New DM, West AP Jr, Bjorkman PJ. Anti-PolyQ antibodies recognize a short polyQ stretch in both normal and mutant huntingtin exon 1. J Mol Biol 2015;427(15):2507-2519.
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