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Comment
. 2021 Jan 15;2(1):14-15.
doi: 10.1016/j.medj.2020.12.014.

Pathways from Immune Profiling to Therapies for Rare Diseases

Averil Ma  1
Affiliations
Free article
Comment

Pathways from Immune Profiling to Therapies for Rare Diseases

Averil Ma. Med. .
Free article

Abstract

Single-cell transcriptomic profiling has enhanced the description of several diseases. Beyond improving our understanding of the pathophysiology of these diseases, these approaches can lead to clues about therapeutic approaches. In a recent issue of Cell, Wang et al. describe immune perturbations in livers of biliary atresia patients that implicate specific autoimmune pathways of disease.1.

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Conflict of interest statement

Declaration of Interests The author declares no competing interests.

Comment on

  • Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.
    Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, Xu Y, Wu Q, Guo X, Nie J, Lu B, Huang B, Xian H, Wang X, Wu Q, Zeng J, Chai C, Zhang M, Lin Y, Zhang L, Zhao S, Tong Y, Zeng L, Gu X, Chen ZG, Yi S, Zhang T, Delfouneso D, Zhang Y, Nutt SL, Lew AM, Lu L, Bai F, Xia H, Wen Z, Zhang Y. Wang J, et al. Cell. 2020 Dec 23;183(7):1867-1883.e26. doi: 10.1016/j.cell.2020.10.048. Epub 2020 Nov 27. Cell. 2020. PMID: 33248023

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